Our services

Scientific and regulatory support for drug discovery and development

We provide integrated consultancy in DMPK, toxicology and non-clinical safety, helping biotech and pharmaceutical companies make better decisions, reduce risk and accelerate development timelines.

Key services

Clear strategy for complex scientific and regulatory challenges

ADME screening and lead optimisation

Design and optimisation of ADME screening cascades from hit-to-lead to candidate selection.

  • Design and optimisation of ADME screening cascades from hit-to-lead to candidate selection. Includes hit-to-lead support, lead optimisation strategy, ADME cascade design and scientific interpretation of screening data.

IND-enabling programmes

Strategic support for non-clinical packages required to progress towards first-in-human studies.

  • Strategic support for non-clinical packages required to progress towards first-in-human studies. Includes IND-enabling study planning, non-clinical safety packages, FIH readiness support and CRO selection and oversight.

Development strategy

Integrated scientific support to select the right candidate and build a robust development strategy.

  • Integrated scientific support to select the right candidate and build a robust development strategy. Includes candidate selection criteria, DMPK and toxicology integration, risk-based development planning and decision-making support.

Regulatory documents and agency interactions

Preparation and scientific support for regulatory documentation and interactions with agencies.

  • Preparation and scientific support for regulatory documentation and interactions with agencies. Includes briefing documents, scientific advice preparation, EMA and FDA aligned strategy and response preparation.

Due diligence and second opinions

Independent scientific review for investors, biotech leadership and business development teams.

  • Independent scientific review for investors, biotech leadership and business development teams. Includes licensing support, asset evaluation, portfolio review and scientific risk assessment.

Risk assessment and mitigation

Early identification of potential DMPK, toxicology and regulatory risks across discovery and development.

  • Early identification of potential DMPK, toxicology and regulatory risks across discovery and development. Includes gap analysis, risk mitigation plans, exposure-response interpretation and development remediation strategy.
Expertise areas

Specialised scientific and regulatory consultancy

Pharmacokinetics, drug metabolism and toxicology

We support programmes from hit identification through to clinical development and registration.

  • ADME screening cascade design
  • Candidate selection support
  • Full DMPK and toxicology support
  • Strategic study design
  • CRO selection and outsourcing
  • Expert scientific oversight

Regulatory interactions

We provide strategic and hands-on regulatory support aligned with EMA and FDA expectations.

  • Clinical pharmacokinetics strategy
  • Toxicology and safety pharmacology strategy
  • Dose justification
  • Exposure-response analysis
  • DDI risk assessment
  • Special population strategy

Strategic and business support

Independent scientific insight for investors, biotech leadership and business development teams.

  • Due diligence for licensing and acquisitions
  • Portfolio and asset evaluation
  • Risk assessment and mitigation
  • Board and investor discussion support
  • EU/US development strategy alignment
How we work

A pragmatic, data-driven and client-focused approach

01

Understand

We review your scientific, regulatory and development context to identify the key challenges.

02

Analyse

We assess DMPK, toxicology and non-clinical safety data to identify gaps, risks and opportunities.

03

Strategise

We translate complex data into clear development and regulatory strategies.

04

Support

We provide ongoing scientific guidance, documentation support and agency interaction preparation.

Need strategic scientific support?

Let’s discuss how MS Pharma Consulting can support your programme.

Contact us